Michele Schlich is affiliated researcher at the Nanotechnology for Precision Medicine laboratory at Istituto Italiano di Tecnologia, and post doc at the University of Cagliari. His research is focused on the design, production and characterization of nanocarriers for small molecules and nucleic acid delivery. He is currently working on the formulation of lipid-based nanoparticles for oligonucleotides and proteins delivery, exploring their application for the treatment of brain cancer and for vaccination, respectively.
Dr Schlich obtained his PhD in Life, Environmental and Drug Sciences at the University of Cagliari in April 2017. During his PhD, he worked on the development of liposome and cyclodextrin-based nanocarriers encapsulating siRNA against neurodegeneration and brain cancer. His research interests also involve the formulation of nanosuspensions to increase the dermal and transdermal bioavailability of poorly soluble drugs, as well as the combination of nanomedicines with medical devices (eg. needle-free jet injectors, microneedle rollers) to improve safety and efficacy. As a part of his training, dr Schlich has been a visiting researcher at the School of Pharmacy of the University College Cork (2015-2016), working on non-viral vectors for siRNA delivery and their biological testing, and a visiting student at the Department of Organic Chemistry of the Semmelweis University, Budapest (2011-2012).